Measuring LRRK2 kinase levels with Sandwich-ELISA in an in vivo viral model of LRRK2-associated Parkinson’s disease.
- Title
- Measuring LRRK2 kinase levels with Sandwich-ELISA in an in vivo viral model of LRRK2-associated Parkinson’s disease.
- Creator
- Tsiakou, Ifigeneia
- Abstract
- The project is about the measurement of LRRK2 kinase levels in striatum with Sandwich-ELISA in an in vivo viral model of LRRK2-associated Parkinson’s disease. LRRK2 is a protein, encoded by the LRRK2 gene and the variants of this gene are associated with familial and idiopathic Parkinson’s disease (PD). The importance of LRRK2 levels and their relationship to PD pathogenesis is crucial for understanding underlying mechanisms of the disease and such models are crucial to test new LRRK2-targeted treatments for PD.
- Keywords
- LRRK2
- Parkinson’s disease
- Biomarker
- Subject
- Biomedical Sciences
- Date Available
- June 10, 2024
- Type
- Poster
- Course
- BMS 4650 Capstone in Biomedical Sciences
- Instructor
- Polissidis, Alexia
- Session
- Poster Display
- Location
- Student Lounge